''Subcutaneous Administration Of Testosterone'' a study with low dose

Got this from the Michael Scally MD blog

Al-Futaisi AM, Al-Zakwani IS, Almahrezi AM, Morris D. Subcutaneous administration of testosterone. A pilot study report. Saudi Med J 2006;27(12):1843-6. http://ipac.kacst.edu.sa/eDoc/2006/161440_1.pdf

OBJECTIVE: To investigate the effect of low doses of subcutaneous testosterone in hypogonadal men since the intramuscular route, which is the most widely used form of testosterone replacement therapy, is inconvenient to many patients.

METHODS: All men with primary and secondary hypogonadism attending the reproductive endocrine clinic at Royal Victoria Hospital, Monteral, Quebec, Canada, were invited to participate in the study. Subjects were enrolled from January 2002 till December 2002. Patients were asked to self-administer weekly low doses of testosterone enanthate using 0.5 ml insulin syringe.

RESULTS: A total of 22 patients were enrolled in the study. The mean trough was 14.48 +/- 3.14 nmol/L and peak total testosterone was 21.65 +/- 7.32 nmol/L. For the free testosterone the average trough was 59.94 +/- 20.60 pmol/L and the peak was 85.17 +/- 32.88 pmol/L. All of the patients delivered testosterone with ease and no local reactions were reported.

CONCLUSION: Therapy with weekly subcutaneous testosterone produced serum levels that were within the normal range in 100% of patients for both peak and trough levels. This is the first report, which demonstrated the efficacy of delivering weekly testosterone using this cheap, safe, and less painful subcutaneous route.

NB: the low doses it refers to was an average of 55, with a max of 100mg.
NB 2: Obviously this is a very low dose, but it makes you wonder how effective it would be for doses up to 500mg (or 2x 250mg since subQ spots are plentiful). Could be an easy alternative for those who aren't keen on intramuscular injections

 

''Subcutaneous Administration Of Testosterone'' a study with low dose

how do the peaks and numbers of test in the system stand up again IM shots ?

is sub-q and IM giving the same test level give or take ?

if sub-q was as good as IM i would probably shoot 250mg eod sub-q .

 

''Subcutaneous Administration Of Testosterone'' a study with low dose

That's the question... if efficacy is similar then it's all good IMO, as subcut jabs are a breeze and not anywhere close to the PIP of an intramuscular shot.

 

''Subcutaneous Administration Of Testosterone'' a study with low dose

makes you wonder what sub-q pip would be like .

amm i daft enough to get a vial of that pippy stuff and try it

 

''Subcutaneous Administration Of Testosterone'' a study with low dose

i shoot test 400 sub cut on cruise.....it is a fiddle putting oil through a small needle and i back fill obv too

i only ever put .25ml in any site or it can get lumpy short term and sting

on a gram plus ew - it would not be practicle imo - i just get in in deep

 

''Subcutaneous Administration Of Testosterone'' a study with low dose

do you use a slin pin as you would hcg or mt2 ? .

 

''Subcutaneous Administration Of Testosterone'' a study with low dose

Im sure J1mmy did a few subq shots and it formed a lump for a few weeks/months

 

''Subcutaneous Administration Of Testosterone'' a study with low dose

apple used to jab sub-q he aquired some lumps also but not sure how much was being pinned .

 

''Subcutaneous Administration Of Testosterone'' a study with low dose

I'd imagine there would be complications with the amount of oil a shot of test/deca/whatever is compared to 0.1ml for MT-2 etc?

 

''Subcutaneous Administration Of Testosterone'' a study with low dose

like ?